Learning objectives
1. Objective of case-control studies
2. Principles
3. Types of case-control studies
4. Setting up case-control studies
4.1 Cases definition
4.2 Selecting cases
4.3 Control definition
4.4 Selecting controls
4.5 Number of controls per case
5. Special cases
5.1 Several control groups
5.2 Matching
6. Data gathering
6.1 Information on the disease
6.2 Information on exposure
7. Analysis
7.1 Introduction
7.2 Definition of the Odds-ratio
7.3 Calculating the Odds-ratio
7.4 Interpretation of the Odds-ratio
7.5 95% Confidence Interval
8. Potential biases
8.1 What is a bias?
8.2 Two major types of biases
8.3 Selection biases
8.4 Misclassification biases
9. Examples of case-control studies
10. Conclusion
10.1 Advantages of case-control studies
10.2 Limitations of case-control studies
10.3 Summary
Test yourself!