Beyond Efficacy: The full public health impact of Vaccines in addition to efficacy measured in trials

  • Venue: Conference Center les Pensières (Annecy)

  • Date: 22 - 24 June 2015

  • Posted: 06/03/2015

  • Theme: Prevention and Vaccines

  • Type: Course and conference

  • Language: English

Vaccine efficacy reflects the proportionate reduction in disease incidence between unvaccinated and vaccinated individuals. While vaccines are typically licensed on the basis of demonstrated efficacy, the ultimate goal of vaccination is to achieve a significant public health impact in addition to the prevention of infection in an individual. In this respect, there is a need to provide a broader perspective that encompasses the capacity of a vaccination program to reduce microbial transmission, avert disease, disability and premature deaths, and to lessen the pressure on health system and to reduce health inequities between populations. These issues are particularly relevant for some of the newer vaccines (e.g., rotavirus, dengue, and malaria vaccines) that demonstrate lower efficacy in high burden settings than traditional vaccines, but nevertheless could have a substantial overall public health impact in these settings.

The objectives of the meeting is to discuss how to integrate vaccine efficacy/effectiveness with preventable disease burden: 1. in the context of vaccine licensure 2. in the context of developing evidence-based immunization program policy for public sector vaccination programs 3. in the context of developing communication strategies for target populations.

Download the Programme [1.24 Mo PDF]

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